485mg Berberine HCl per cap from 500mg Berberis aristata extract
Supplement Needs Berberine delivers 485mg berberine HCl per capsule from a fully disclosed 500mg Berberis aristata 10:1 root extract, standardised to 97% berberine alkaloids. The 60-capsule pack provides 60 daily servings. No proprietary blends, full active dose on the label.
Berberine is an isoquinoline alkaloid derived from the Berberis genus. It activates AMP-activated protein kinase (AMPK), a cellular energy sensor that plays a central role in glucose metabolism, insulin sensitivity and fatty acid oxidation. Multiple clinical studies have investigated berberine for blood glucose management and lipid metabolism, with the most consistent evidence at daily doses of 1000-1500mg - three 485mg capsules approximate this range when dosed according to protocol. The bioavailability of berberine is increased when taken with food and can be supported by concurrent use of piperine (found in Supplement Needs TUDCA & NAC or Curcumin products).
Supplement Needs positions Berberine within its Health range alongside TUDCA & NAC and Curcumin as part of a metabolic and liver health stack formulated by Dr Dean St Mart. The fully transparent, non-proprietary label approach is a core part of the brand's positioning - every active dose is disclosed so users can verify dosing against research. The 60-cap format provides a one- to two-month supply depending on daily dose.
Built for adults using berberine as part of a structured metabolic health routine - type 2 diabetes management alongside medical supervision, lipid support, or PCOS management. Not suitable as a casual supplement addition without understanding the AMPK mechanism and potential interactions with diabetes medications. Not suitable for children, pregnant or breastfeeding women. No major allergens declared.
Liver-stack alternative: Efectiv Nutrition Organ Support 150 Caps for trainees wanting multi-organ support alongside metabolic markers.