Protein In Brain Seen To Regulate Food Intake & Body Weight Control


The protein of interest is the alpha-2/delta-1 and thus far, it has not been linked to obesity. However, a professor that goes by the name of Maribel Rios Ph.D has discovered a link between alpha-2/delta-1 and another protein called brain derived neurotrophic factor (BDNF), a protein that is understood to have a major part to play in appetite suppression.

It is well understood that low levels of BDNF can lead to overeating and obesity in mice, and it is now thought that this probably translates to humans too. The interesting finding is this…the alpha-2/delta-1 is evidently necessary for the normal functioning of BDNF meaning we could harness this and apply a new directive for the treatment of obesity! The findings of the study found that low levels of BDNF were directly associated with a reduced function of alpha-2/delta-1  in the hypothalamus region of the brain (a region that is synonymous with appetite and weight).

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Science Daily, (2014). Your source for the latest research news. Neuroscience study uncovers new player in obesity. Retrieved 10th January, 2013, from   

About the Author

Job Role Qualified Dietitian and Sports Nutritionist Qualifications BSc (Hons) Sports Science | BSc (Hons) Dietetics Tom has always participated in sport both recreationally and competitively which led to an unquenchable thirst for information on anything health, nutrition and fitness. After leaving school Tom went on to play for a football academy during which time he studied Sport and Exercise Science. From here he went on to study a BSc (Hons) Sport Science at UEA followed by his second BSc (Hons) degree, this time at the University of Hertfordshire studying Dietetics. Tom has worked in the fitness, educational and clinical nutrition industry starting out at David Lloyd Health and Leisure Clubs. He then went on to work as a Dietitian (RD) in the NHS, during which time he conducted clinics for healthy eating, weight loss and weight gain, as well as specialised consultations on Diabetes, IBS and Coeliac disease to name a few. He has vast amounts of experience at devising diet plans and supplement regimens, as well as working in the community with schools and competitive athletes. As Head Nutritionist and Supplement expert at Discount Supplements Tom is here to provide current and evidence based health and nutrition information to help you reach your health and fitness goals!
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