Conscious to be clear from the outset, let me start by saying you should always exercise caution when ‘combining’ any supplement or nutritional ingredient, especially a pre- workout or something that acts directly on the cardiovascular system. However there are many supplement companies who have made things a lot easier (and safer) for you as the consumer. Recent research from an animal study by Kyowa Hakko reinforces the thought that L- arginine and L- citrulline could work cumulatively together, this combo evidently increases plasma L- arginine levels which enhances nitric oxide availability to the major organs and muscle.
Not only would the increased nitric oxide release improve training performance due to vasodilation (widened blood vessels), elevated oxygen delivery and carbon dioxide removal, it may also help overall health. More specifically, the researchers believe that the combination of L- arginine and L- citrulline could help to offset the effects of endothelial dysfunction, a condition where the inner lining of blood vessels become less receptive to nitric oxide, consequently they don’t dilate as they should in turn hindering blood flow. This reduced blood flow may also be an early initiating factor in cardiovascular disease (heart problems).
By no means is this study saying you HAVE to consume these ingredients to stay healthy, the real finding is that the two ingredients might ultimately improve blood flow, heart health and of course…training potential!
Nutringredients.com, (2015). Study: L-arginine/L-citrulline combo outperforms either amino acid in isolation for NO activity. Retrieved 6th May, 2015, from http://www.nutraingredients.com/Research/Study-L-arginine-L-citrulline-combo-outperforms-either-amino-acid-in-isolation-for-NO-activity/?utm_source=newsletter_daily&utm_medium=email&utm_campaign=28-Apr-2015&c=FN21qK%2FOpvKSCnZEzZ690G3ET%2Fyj%2FSSi&