It is a widely accepted rule in science and research that you must NEVER take the findings of one research paper as absolute, irrefutable fact. It is imperative that we consider the overall body of information before we come to an agreed conclusion on a subject matter. However, sometimes, if we're sensible, we can make educated assumptions...
Most research findings stem from a previous repository of accepted knowledge, meaning we can make a reasonably well substantiated claim that ‘x’ will end in ‘y’. A good example of this is Creatine and its role in the functioning of heart tissue. Creatine is used as an energy source in the creatine kinase system, which is an energy source to the heart, therefore it is not unreasonable to suggest that creatine supplementation may feed into the functioning of the heart in one way or another.
Dr Theo Wallimann explains how an ageing heart contains considerably less phosphocreatine and ATP (your bodies main energy currency), which negatively effects the energy pathways and overall efficiency of the heart. Now although research has shown that creatine supplementation has little effect on cardiac output, the ability of creatine to strengthen overall muscle tissue did improve quality of life. So indirectly then, creatine supplementation can enable people to be more active, which in turn supports the daily function of the heart and related energy systems.
Source
Wallimann, T, A. (2012). Creatine for the heart, bones, brain and the nervous system. Medical Sports Network. Succidia.
NOTE: If you have an underlying heart condition of any sort, it is prudent to contact your Doctor first before commencing a nutrition supplement regime