1000ug VITAMIN B12 per tablet
Applied Nutrition Vitamin B12 1000mcg is a 90-capsule high-strength B12 supplement. Each 1-capsule serving delivers 1000ug (1000mcg) of vitamin B12 (cobalamin), which is 40,000% of the EU Nutrient Reference Value. The 90-cap bottle provides a 90-day supply. Vitamin B12 at this dose qualifies for the following EU-authorised health claims under Regulation 432/2012:
- Vitamin B12 1000ug (40,000% NRV) - contributes to normal energy-yielding metabolism, the normal function of the immune system, normal psychological function, a reduction of tiredness and fatigue, normal functioning of the nervous system, normal homocysteine metabolism, normal red blood cell formation, and the process of cell division.
The 1000ug dose is deliberate. B12 absorption from oral supplements is largely passive diffusion — a mechanism that is inherently low-efficiency, absorbing approximately 1-2% of the dose. At 1000ug, passive absorption delivers approximately 10-15ug of active B12, which exceeds the NRV (2.5ug) by a meaningful margin and provides a practical buffer for individuals with suboptimal intrinsic factor production. This is why high-dose B12 is the clinical standard for oral supplementation, particularly in older adults.
Built for vegans and vegetarians (B12 is found almost exclusively in animal products), adults over 50 (intrinsic factor production declines with age), individuals with low stomach acid or taking proton pump inhibitors, and active adults experiencing persistent tiredness despite adequate sleep. Applied Nutrition own-brand value tier: 90 days supply of 1000ug B12 at one of the most competitive price points in the category.
