THP Fisetin 100mg, 98% Pure Smoke Tree Extract for Cellular Health and Antioxidant Support
The Health Project Fisetin is a high-purity plant polyphenol supplement in capsule form. Each capsule delivers 100mg of Fisetin at 98% purity, extracted from Smoke Tree (Cotinus coggygria). The 90-capsule bottle provides 90 single-capsule servings.
Fisetin is a flavonol found naturally in strawberries, apples and onions. It has attracted significant research interest across several longevity and cellular health mechanisms: it activates the Sirtuin 1 deacetylase pathway involved in cellular stress resistance and mitochondrial biogenesis; it has demonstrated senolytic activity in vitro and in animal models, selectively inducing apoptosis in senescent cells while sparing healthy cells; it activates Nrf2, the master antioxidant transcription factor driving glutathione synthesis and phase-II detoxification enzyme expression; and it crosses the blood-brain barrier where it provides neuroprotective effects through reduction of neuroinflammation. The Smoke Tree source is the highest-fisetin-density botanical available commercially.
What separates THP Fisetin from a general antioxidant capsule is the senolytic mechanism. Standard antioxidants neutralise reactive oxygen species extracellularly or cytoplasm-wide. Fisetin selectively targets senescent cells for clearance - a mechanistically distinct intervention relevant to cellular health maintenance and longevity science that standard antioxidants do not address.
THP Fisetin suits health-optimising individuals interested in longevity pathway support, athletes looking to support cellular health and mitochondrial function, and anyone researching evidence-emerging plant polyphenols for comprehensive wellness protocols. It is not a medical treatment and should not be interpreted as such. Contains no major allergens.