High-Strength Vitamin D3
4000IU D3 + 100ug K2 per capsule
Applied Nutrition Vitamin D3 & K2 60 Caps - 60 Caps
Applied Nutrition

Applied Nutrition Vitamin D3 & K2 60 Caps

★★★★★
| 0 reviews |  60 Servings
£6.99 £9.99 £0.12/serving
4000IU (100ug) Vitamin D3 Per Capsule 4000IU vitamin D3 (cholecalciferol) per capsule - a high-strength daily dose, ten times the UK NRV of 5ug, designed for adults seeking robust D3 support through winter and limited-sunlight months.
100ug Vitamin K2 (MK-7 Form) 100ug vitamin K2 as menaquinone-7 (MK-7) - the longer-half-life form preferred for daily dosing. K2 supports normal blood clotting and the maintenance of normal bones.
D3 + K2 Synergy, One Capsule Daily D3 and K2 are commonly paired for bone-mineral and cardiovascular support. 60-capsule pack = roughly two months' supply at one capsule per day. Daily dose printed on the tub.
Size 60 Caps
Standard delivery
Next day (£5.99)
17,600+ Reviews
14-Day Returns
Est. 2005
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Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle. If you are pregnant, breastfeeding, taking medication, or under medical supervision, consult your doctor before use. Do not exceed the recommended daily intake. Store out of reach of children.

60 Caps Out of stock

4000IU Vitamin D3 + 100ug K2 (MK-7)

Applied Nutrition Vitamin D3 + K2 is a 60-capsule daily combination supplement. Each 1-capsule serving delivers 4000IU (100ug) of vitamin D3 and 100ug of vitamin K2 as MK-7. The combination qualifies for the following EU-authorised health claims under Regulation 432/2012:

- Vitamin D3 100ug / 4000IU (2000% NRV) - contributes to normal muscle function, the maintenance of normal bones, normal calcium and phosphorus absorption, normal blood calcium levels, the normal function of the immune system, and the maintenance of normal teeth.

- Vitamin K2 100ug (133% NRV) - vitamin K contributes to normal blood clotting and to the maintenance of normal bones. The MK-7 form (menaquinone-7) is the most bioavailable vitamin K2 isomer and has the longest half-life of any K2 form, supporting sustained serum activity from a single daily dose.

D3 and K2 are combined because they work on the same metabolic axis. Vitamin D3 increases intestinal calcium absorption; vitamin K2 (as MK-7) activates osteocalcin and matrix GLA protein, directing calcium toward bone and away from arterial tissue. Supplementing D3 without K2 raises serum calcium; K2 determines where that calcium is deposited. The combination is standard practice in clinical supplementation protocols for bone and cardiovascular health.

Built for adults over 30, post-menopausal women, and athletes in heavy loading phases who want both vitamin D repletion and K2-mediated calcium control in one capsule. Applied Nutrition own-brand value tier: a targeted two-ingredient formula at a dose typical of specialist D3+K2 products.

Alternative: Efectiv Nutrition Vitamin D3 K2 60 Caps for trainees wanting the D3 + K2 combo from an own-brand supplier.

Key Benefits

Synergistic Formula

D3 and K2 work together - D3 helps absorb calcium while K2 directs it to bones.

Bone Health

Supports the maintenance of normal bones by optimising calcium utilisation.

Immune Support

Vitamin D3 contributes to the normal function of the immune system.

Cardiovascular

Vitamin K2 helps keep calcium in bones and out of arteries.

Frequently Asked Questions

How much Vitamin D3 is in each capsule?

Each capsule provides 100ug of vitamin D3 (cholecalciferol), which equals 4000IU. This is a high-strength daily dose - ten times the UK NRV of 5ug (200IU) - intended for adults. Paired with 100ug of vitamin K2 in the MK-7 form. 60 capsules per bottle.

When should I take Vitamin D3 & K2?

D3 and K2 are both fat-soluble, so take one capsule daily with a meal containing some fat for better absorption. Many people take it with breakfast or lunch. Consistent daily use over time matters more than precise timing.

Why combine D3 and K2 in one capsule?

Vitamin D3 supports calcium absorption from the gut. Vitamin K2 (MK-7 form) supports normal blood clotting and the maintenance of normal bones. They are commonly paired in a single capsule because they are both fat-soluble, both taken once a day with food, and both used in bone and cardiovascular support stacks. The combination is convenience-driven; you do not have to take them together for either vitamin to work.